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Characterization of Rhizobium loti strains native from the Salado River Basin. Studies on symbiotic potential.

Mónica M. Fulchieri; M. Julia Estrella and Alberto A. Iglesias

Instituto Tecnológico de Chascomús (INTECH-CONICET)
Camino Circunvalación Laguna km 6, C.C. 164
Chascomús 7130. Argentina.

Introduction.
The Salado River Basin is an extensive area in Buenos Aires province (Argentina). Soils in this area are characterized by a high salinity, being poorly drained and periodically exposed to waterlogged conditions. The region is mainly utilized for beef and dairy cattle production, with principal feed for these purposes represented by native grassland and naturalized Lotus glaber (Montes 1987). Lotus is a legume associated, in a symbiotic way, with bacteria belonging to the genus Rhizobium loti, thus producing root nodules where the nitrogen fixation process occurs. R. loti strains commonly found in soils of the Salado River Basin are capable of forming nodules quite specifically with L. glaber (Estrella et al. 1997). However, the characterization of native R. loti strains was not performed and data concerning the potential symbiotic capacity of these strains are not currently available.

Rhizobium loti-legume host association shows some characteristics which are different from those exhibited by other nitrogen fixation systems. Rhizobia nodulating Lotus species include both fast-and slow-growing strains (Irisarri et al. 1996; Jordan et al. 1984), and those strains of R. loti so far examined exhibit symbiotic promiscuity as they establish N2-fixing association not only with Lotus spp., but also with a variety of other legumes (Sullivant et al. 1996).

The purpose of this work was to obtain information about native R. loti population found in Chascomús, a representative area of the Salado River Basin region, to determine the symbiotic potential of different isolate strains and to characterize them by establishing a comparison with other isolates from the region and with collection strains. The long range objective of our work is to develop technological tools to obtain good forage species and the corresponding Rhizobium strain to optimize productivity and economic efficiency in the zone.

Material and Methods

Organisms and maintenance of cultures
Strains of Rhizobium were originally isolated from nodules of L. glaber plants naturally growing in: i) the outskirts of Chascomús city, strains 1-INTECh, 2-INTECh, 3-INTECh, 4-INTECh; ii) two different sites of the Salado River Basin area, strains Pirán (from Pirán) and Ayac (from Ayacucho); and iii) reference strains of Rhizobium Culture Collection (kindly gifted by Dr. Esperanza Martinez-Romero, Centro de Investigación sobre Fijación de Nitrógeno, UNAM, Cuernavaca, Mexico). All bacteria were cultured in YEM medium (Vincent 1970), at 28 ºC with rotator shaking.

Generation times and acid production
Doubling times were calculated from the exponential growth phase of cultures according to Martínez de Drets et al. (1974), by reading optical density (A= 620 nm) every 1 h. Native isolates and reference strains were examined for acid or alkaline production after growth for 2 days (fast-growing isolates) or 6 days (slow-growing isolates) as indicated earlier (Monza et al. 1992).

Carbon source utilization
For determination of carbon source utilization, cultured cells were collected by 4 min centrifugation at 8000 rmp (4ºC), washed twice with PBS buffer (20 mM sodium phosphate, pH 7.0, 150 mM NaCl and 3 mM KCl) and finally resuspended in the mineral medium (MM) described by Vincent (1970), containing appropriate carbon source at a final concentration of (5 mg/ml). Utilization of monosaccharides (D-glucose, D-galactose), polyols (glycerol and mannitol), disaccharides (raphinose and sucrose), carboxylic acids (succinate, citrate) and aromatic compounds (ferulic acid and cumaric acid) was determined as described by Arias et al. (1979). When aromatic compounds were used as carbon sources, stock solutions were prepared in ethanol and added to the mineral medium at a final concentration of 20 mM.

Results and discussion.
The generation time of 6 native isolates from nodulated L. glaber are presented in Table 1. Rhizobium loti NZP2227 and Bradyrhizobium loti NZP 2309 were used as reference strains for fast and slow-growing rhizobia, respectively. R. loti strain used as commercial inoculant for Lotus spp. was also assayed for comparative studies. As shown, the reference strain NZP2227 and two of the isolates (1-INTECh and 4-INTECh) exhibited fast growth rates, ranging from 2.4 to 5.4 h. The isolates 2-INTECh and 3-INTECh showed intermediate growth rates of 8.3 and 7.2, respectively. The remaining isolates from the region (Ayac and Pirán) and the commercial R. loti showed growth rates ranging from 10.5 to 11.9 h, and thus included with the slow-growing reference strain NZP2309 (16.3 h) (Table 1).

Table 1. Generation time and carbon utilization for the different rhizobia isolates from Chascomús and the Salado River Basin as well as for reference strains and commercial R. loti utilized for a comparison. Abbreviations are: Glc, glucose; Gal, galactose; Gly, glycerol; Man, mannitol; Suc, sucrose; Rap, raphinose; Citr, citrate; Succ, succinate; Fer, ferulic acid; Cum, cumaric acid.
Growth (+); no growth (-); nd, not determined.


Carbon source
Monosaccharides
Polyols
Disaccharides
Carboxylic acids
Aromatic compounds
Strain
Generation time (h)
Glc
Gal
Gly
Man
Suc
Rap
Citr
Succ
Fer
Cum
NZP2227
5.4 ± 0.2
+
+
+
+
+
+
-
+
+
-
NZP2309
16.3 ± 0.2
+
+
+
+
-
-
+
+
+
+
1-INTECh
5.0 ± 0.1
+
+
+
+
+
+
-
+
+
-
2-INTECh
8.3 ± 0.1
+
+
+
+
+
+
-
+
+
+
3-INTECh
7.2 ± 0.2
+
+
+
+
+
+
-
+
-
-
4-INTECh
2.4 ± 0.3
+
+
+
+
+
+
-
+
+
-
Ayac
11.7 ± 0.3
+
+
+
+
-
-
+
+
+
+
Pirán
10.5 ± 0.2
+
+
+
+
+
+
+
+
+
+
Commerc.

R. loti
11.9 ± 0.4
+
+
+
+
+
+
+
+
nd
nd

On the other hand, only the strain NZP2227 and the isolates 1-INTECh and 4-INTECh produced an acid reaction in YEM medium (data not shown). This is consistent with previous results indicating that fast-growing R. loti strains are able to acidify the growth medium (Monza et al. 1992). All other isolates, as well as the slow-growing reference strain NZP2309 did not produce any significant change in pH the medium (data not shown).

As also shown in Table 1, no differences in the utilization of monosaccharides were observed among isolates. All of them grew well with either D-glucose or D-galactose, as the only carbon source. Similarly, all rhizobial cells tested were able to grow on mineral medium with either glycerol or mannitol (Table 1). It has been shown that fast- and slow-growing species of the Rhizobiaceae can use a variety of disaccharides, being the utilization of this carbon source a possible criterion to distinguish between Rhizobium and Bradyrhizobium strains (Jordan et al. 1984; Martinez de Drets et al. 1974). In our hands, all the isolates utilized both, sucrose and raphinose; except for the strain Ayac, which behaved as the reference Bradyrhizobium NZP2309 according to this criterion (Table 1).

Among carboxylic acids, succinate allowed growing of all the isolates, while citrate supported growing of slow-growing but not of the fast-growing strains (Table 1). It is interesting to note that the slow-growers strains Pirán and Ayac and the intermediate-grower 2-INTECh utilized cumaric acid, thus exhibiting a similar behaviour than the strain Bradyrhizobium loti NZP2309 (Table 1). This is consistent with other reports indicating that the ability to use aromatic compounds is widespread among slow-growing species of the Rhizobiaceae (Stower et al. 1995; Irisarri et al. 1996).

Our results, based on plant specificity, doubling time, carbon source utilization and acid production indicate that native isolates from the Chascomús area are predominantly intermediate and fast-growers, in difference with strains from other zones of the Salado River Basin region and the commercial R. loti utilized as inoculant, which are slow-growers. Although more information about the native isolates is required, preliminary results indicate that from them and from new isolates it is possible to obtain adequate strains to improve N2-fixation in Lotus cultivars in the region.

Acknowledgments.
This work was supported, in part, by grants from the Comisión de Investigaciones Científicas (CIC, Buenos Aires). MMF and AAI are research career members from Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET, Argentina).

References.

Arias A., Cervenansky C., Gardiol A. and Martinez-Drets G. (1979) Phosphoglucose isomerase mutant of Rhizobium meliloti. J. Bacteriol. 137: 409-414.

Estrella M.J.; Pieckenstain F., Ugalde R.A. and Iglesias A.A. (1997) Studies on the symbiotic potential of a Rhizobium loti strain native from Chasomús on Lotus pedunculatus and Lotus corniculatus var. hirsutus plants" Lotus Newslett. 28, http://www.plantsci.missouri.edu/lnl

Irisarri P., Milnitsky, Monza J and Bedmar E.J. (1996) Characterization of rhizobia nodulating Lotus subbiflorus from uruguayan soil. Plant and Soil 180: 39-47.

Jordan D. C. (1984) Gram-negative aerobic rods and cocci. Family III Rhizobiaceae. In Bergey's Manual of Systematic Bacteriology. Eds. N. Krieg and J.G. Holt, pp. 234-244. Williams and Wilkins, Bartimore, USA.

Martínez de Drets G., Arias A. and Rovira de Cutinella M. (1974) Fast- and slow-growing rhizobia: differences in sucrose utilization and invertase activity. Can. J. Microbiol. 20: 605-609.

Montes L. (1987) Current research on Lotus tenuis in Balcarce (Argentina). Lotus Newslett. 18:13.

Monza J., Fabiano E. and Arias A. (1992) Characterization of an indigenous population of rhizobia nodulating Lotus corniculatus. Soil Biol. Biochem. 24: 241-247.

Sullivan J.T., Eaardly B. D., van Bercum P. and Ronson C. (1996) Four unnamed species of nonsymbiotic rhizobia isolated from the rhizosphere of Lotus corniculatus. Appl. Environ. Microbiol. 62: 2818-2825.

Stower M.D. (1995) Carbon metabolism in Rhizobium species. Annu. Rev. Microbiol. 39: 89-108.

Vincent J.M. (1970) A manual for the practical study of the root-nodule bacteria. I.B.P. Handbook No. 15, Blackwell, Oxford.

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